Welcome to XERF, a new era in RF Skin Tightening

The future of skincare has arrived with XERF ™ a breakthrough Structural Skin Tightening machine that delivers the collagen-stimulating benefits of radio frequency without the need for numbing, injections, or recovery time. Unlike existing RF treatments, the XERF™ technology penetrates more deeply, targeting the surface, mid, and foundational layers of the skin—where lasting transformation truly starts.

Transformative
Results & No Sacrifice

• Non-Invasive: Nonumbing, no needles, and no downtime.

• Structural Skin Tightening: Delivering RF energy to structural skin layers – boosting collagen where it counts.

• Fully customizable treatments: Three depth setting and ten intensity levels.

How XERF Structural Skin Tightening works


The XERF system offers the world’s first multifrequency monopolar RF skin tightening treatment, by combining both 6.78 MHz and 2 MHz frequencies. XERF can deliver energy not just deeper, but at the structural layer creating smoother tighter and rejuvenated skin. The XERF system leverages Wave Fit™ pulse and advanced integrated cryogen cooling technology to control energy delivery, while maintaining surface temperature, for a Never-Numb™ treatment. The advanced XERF technology requires shorter sessions compared to existing, similar, skin tightening machines potentially increasing the number of patients that can be treated per day.

A Truly Customisable RF Skin Tightening Treatment


No two individuals are alike, and their skin treatments shouldn’t be either. The XERF system adapts to each patient’s unique skin profile using Accurate Impedance Feedback for real-time analysis of the skin. With three depth settings and ten intensity levels, you can truly customise the XERF skin tightening treatment for all your patients.

XERF is the world’s first multifrequency monopolar RF skin tightening treatment. No needles, no numbing, and no downtime – just smoother and tighter skin, personalised for each patient.

The world’s first multifrequency monopolar RF treatment, The XERF Structural Skin Tightening treatment delivers energy into each patient’s skin exactly where they need it most. No needles, no numbing, and no downtime – just smoother and tighter skin, personalized for each patient.

FAQs

In in-vivo studies, Cynosure Lutronic measured internal skin temperatures of 50°C, 60°C, and 70°C using ultrasound-guided fiber-optic imaging. Following the XERF treatment, histological analysis confirmed collagen remodeling.

Histological evidence from in-vivo porcine studies shows increased thickening and tightening of collagen bundles at multiple tissue depths, along with an observable upward pull in the fascia.

Histological analysis from multiple clinical studies confirms the XERF system delivers RF energy to the SMAS (Superficial Musculoaponeurotic System). The SMAS is a foundational tissue layer beneath the skin that plays a key role in lifting and tightening sagging skin and reducing the appearance of jowls.

While there’s no universally agreed-upon timeline, many practitioners recommend waiting between two to six months after facelift surgery before undergoing energy-based skin tightening. This guidance is largely anecdotal and varies depending on individual healing and the specific procedure performed. 

Some patients may notice mild redness or swelling immediately after treatment, but these effects typically subside within 24 hours.

To prolong the benefits of XERF treatment, it’s important to stick to a consistent skincare routine and prioritize sun protection. This means applying a broad-spectrum sunscreen daily, steering clear of harsh or irritating products, and supporting your skin health through a balanced lifestyle.

Achieving optimal results may require a series of sessions, and periodic maintenance treatments can help preserve the improvements over time. Depending on your skin type and treatment plan, the effects of XERF can last anywhere from several weeks to up to three years.

For enhanced and longer-lasting outcomes, XERF can be combined with other non-invasive procedures. This integrated approach helps improve skin tone, texture, and radiance - ensuring your skin stays vibrant and youthful well beyond the initial treatment.

XERF RF skin tightening may be a suitable option if you:

  • Have mild to moderate skin laxity in areas like the lower face or cheeks. The treatment helps improve firmness and reduce fine lines by boosting collagen and elastin production.
  • Prefer a non-surgical solution for skin tightening with minimal downtime. While the procedure is generally comfortable, some people may feel a gentle tingling or vibration during the session.
  • Are recovering from a facelift and want to enhance or maintain results with early-stage rejuvenation.
  1. Dual-Frequency Technology = Enhanced Collagen Activation
    Unlike traditional RF devices that operate on a single frequency (typically 6.78 MHz), XERF combines both 6.78 MHz and 2 MHz. This dual-frequency approach allows energy to reach multiple layers of the skin, promoting deeper and more effective collagen remodelling.
  2. Advanced Cooling System = High Energy with Minimal Risk
    Effective collagen remodelling requires skin temperatures between 55–65°C, but excessive heat can lead to burns or discomfort. XERF’s advanced cooling mechanism delivers up to 12 cooling bursts per shot, enabling higher energy levels while keeping the skin protected and the treatment comfortable.
  3. Larger Treatment Tip = Faster, More Efficient Sessions
  • Standard RF tip size: 4 cm²
  • XERF tip size: 6 cm²
    With a larger surface area, XERF treats more skin with each shot—reducing the number of pulses needed and shortening overall treatment time.

Clinical Evidence

Monopolar radio frequency for dermal temperature regulation and remodeling: A porcine model study

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Efficacy of dual-frequency non-invasive monopolar radio frequency in skin tightening

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One year with XERF – beyond difference, Toward a new standard. Pioneering technology and clinical excellence.

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XERF, the lifting device proven by patient satisfaction – shared by Dr. Wonyoung Toon of Med Clinic

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The XERF device is intended for use in dermatologic and general surgical procedures for electrocoagulation and hemostasis.

All instances of the term “skin tightening” are used to describe tightening effects that occur via soft tissue coagulation.

Cynosure, LLC and Lutronic Aesthetic, Inc. do not diagnose or treat medical conditions, prescribe treatment protocols, provide medical advice, or otherwise practice medicine. Patients should consult with a qualified healthcare professional for diagnosis and proper treatment protocols/parameters to determine if treatment with any product is right for them. Qualified healthcare professionals are responsible for diagnosis and treatment protocols using products.

©2025 CYNOSURE LUTRONIC, INC. All Rights Reserved. Lutronic is a registered trademark and XERF is a trademark of Lutronic Corporation. Cynosure is a registered trademark of Cynosure, LLC.